Article
Paraoxonase 1 (PON1) and stroke; the dilemma of genetic variation.
Clinical biochemistry - 1 Dec 2017
Tajbakhsh Amir, Rezaee Mehdi, Rivandi Mahdi, Forouzanfar Faranak, Afzaljavan Fahimeh, Pasdar Alireza
Abstract excerpt
Ischaemic stroke, which is mostly caused by atherosclerosis, is one of the most widely causes of mortality and morbidity. One of the most important enzymatic activities of paraoxonase-1 (PON1) in association with high-density lipoprotein (HDL) is the prevention of low-density lipoprotein (LDL) oxidation, which gives it an anti-atherogenic activity. PON1 expression and activity is influenced by various factors;...
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