Article
Adaptive laboratory evolution of Pseudomonas putida and Corynebacterium glutamicum to enhance anthranilate tolerance.
Microbiology (Reading, England) - 1 Nov 2020
Kuepper Jannis, Otto Maike, Dickler Jasmin, Behnken Swantje, Magnus Jorgen, Jäger Gernot, Blank Lars M, Wierckx Nick
Abstract excerpt
Microbial bioproduction of the aromatic acid anthranilate (ortho-aminobenzoate) has the potential to replace its current, environmentally demanding production process. The host organism employed for such a process needs to fulfil certain demands to achieve industrially relevant product levels. As anthranilate is toxic for microorganisms, the use of particularly robust production hosts can overcome issues from...
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