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Article

Enhancement of the production of L-glutaminase, an anticancer enzyme, from Aeromonas veronii by adaptive and induced mutation techniques.

PloS one - 1 Jan 2017

Jesuraj S Aravinth Vijay, Sarker Md Moklesur Rahman, Ming Long Chiau, Praya S Marylin Jeya, Ravikumar M, Wui Wong Tin

Abstract excerpt

Microbial anti-cancer enzymes have been proven to be effective and economical agents for cancer treatment. Aeromonas veronii has been identified as a microorganism with the potential to produce L-glutaminase, an anticancer agent effective against acute lymphocytic leukaemia. In this study, a selective medium of Aeromonas veronii was used to culture the microorganism. Strain improvement was done by adaptive and...

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Identifiers

PMID: 28813436
DOI: 10.1371/journal.pone.0181745
PMCID: PMC5558970

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