Article
Phenotype-based single cell sequencing identifies diverse genetic subclones in CD133 positive cancer stem cells.
Biochemical and biophysical research communications - 18 Jun 2021
Min Dong-Wook, Kim Hwang-Phill, Kim Jinhyun, Wen Xianyu, Kim Sungsik, Cho Young-Won, Lim Yoojoo, Song Sang-Hyun, Han Sae-Won, Kwon Sunghoon, Kang Gyeong Hoon, Kim Tae-You
Abstract excerpt
Tumor heterogeneity is one of the ongoing huddles in the field of colon cancer therapy. It is evident that there are countless clones which exhibit different phenotypes and therefore, single cell analysis is inevitable. Cancer stem cells (CSCs) are rare cell population within tumor which is known to function in cancer metastasis and recurrence. Although there have been trials to prove intra-tumoral heterogeneity...
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