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Article

LocusFocus: Web-based colocalization for the annotation and functional follow-up of GWAS.

PLoS computational biology - 1 Oct 2020

Panjwani Naim, Wang Fan, Mastromatteo Scott, Bao Allen, Wang Cheng, He Gengming, Gong Jiafen, Rommens Johanna M, Sun Lei, Strug Lisa J

Abstract excerpt

Genome-wide association studies (GWAS) have primarily identified trait-associated loci in the non-coding genome. Colocalization analyses of SNP associations from GWAS with expression quantitative trait loci (eQTL) evidence enable the generation of hypotheses about responsible mechanism, genes and tissues of origin to guide functional characterization. Here, we present a web-based colocalization browsing and...

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PMID: 33090994
DOI: 10.1371/journal.pcbi.1008336
PMCID: PMC7608978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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