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Article

Human genetics as a tool to identify progranulin regulators.

Journal of molecular neuroscience : MN - 1 Nov 2011

Nicholson Alexandra M, Finch NiCole A, Rademakers Rosa

Abstract excerpt

Frontotemporal lobar degeneration (FTLD) is a common neurodegenerative disorder that predominantly affects individuals under the age of 65. It is known that the most common pathological subtype is FTLD with TAR DNA-binding protein 43 inclusions (FTLD-TDP). FTLD has a strong genetic component with...

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Source

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Identifiers

PMID: 21626010
DOI: 10.1007/s12031-011-9554-y
PMCID: PMC3310391

Genes

GRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21626010-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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