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Epigenetic regulation of ACE2, the receptor of the SARS-CoV-2 virus1

21 Oct 2020

Abstract excerpt

The angiotensin-converting enzyme 2 (ACE2) is the receptor for the three coronaviruses HCoV-NL63, SARS-CoV, and SARS-CoV-2. ACE2 is involved in the regulation of the renin-angiotensin system and blood pressure. ACE2 is also involved in the regulation of several signaling pathways, including integrin signaling. ACE2 expression is regulated transcriptionally and post-transcriptionally. The expression of the gene is...

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PMID: 33086021
DOI: 10.1139/gen-2020-0124

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