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ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives

30 Sept 2020

Abstract excerpt

is subjected to extensive transcriptional and post-transcriptional modulation by epigenetic mechanisms and microRNAs. Also, ACE2 expression is regulated post-translationally by glycosylation, phosphorylation, and shedding from the plasma membrane. ACE2 protein is ubiquitous across mammalian tissues, prominently in the cardiovascular system, kidney, and intestine. ACE2 expression in the respiratory tract is of...

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PMID: 33195436
DOI: 10.3389/fmolb.2020.588618

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