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ACE2: the molecular doorway to SARS-CoV-2

1 Dec 2020

Abstract excerpt

The angiotensin-converting enzyme 2 (ACE2) is the host functional receptor for the new virus SARS-CoV-2 causing Coronavirus Disease 2019. ACE2 is expressed in 72 different cell types. Some factors that can affect the expression of the ACE2 are: sex, environment, comorbidities, medications (e.g. anti-hypertensives) and its interaction with other genes of the renin-angiotensin system and other pathways. Different...

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PMID: 33380340
DOI: 10.1186/s13578-020-00519-8

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