Article
Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways
2021-06-07
Abstract excerpt
The angiotensin-converting enzyme 2 (ACE2) protein has been highly studied as a key catalytic regulator of the renin-angiotensin system (RAS), involved in fluid homeostasis and blood pressure modulation. In addition to its important physiological role as a broadly-expressed membrane-bound protein, ACE2 serves as a cell-surface receptor for some viruses - most notably, coronaviruses such as SARS-CoV and SARS-CoV-2....
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Identifiers and source
- Literature Corpus work
- dbc10f7e-5295-5136-ba07-9c82808d67b9
- DOI
- 10.1101/2021.06.07.447351
