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Article

Emerging Flt3 kinase inhibitors in the treatment of leukaemia.

Expert opinion on emerging drugs - 1 Mar 2006

Tickenbrock Lara, Müller-Tidow Carsten, Berdel Wolfgang E, Serve Hubert

Abstract excerpt

Acute myeloid leukaemia (AML) is characterised by the infiltration of the bone marrow with highly proliferative leukaemic cells that stop to differentiate at different stages of myeloid development and carry survival advantages. Conventionally, AML is treated with aggressive cytotoxic therapy, in...

Topics

Animals
Antineoplastic Agents
Carbazoles
Clinical Trials as Topic
Drug Evaluation, Preclinical
Drug Therapy, Combination
Furans
Humans
Indoles
Leukemia, Myeloid, Acute
Mutation
Protein Kinase Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pyrroles

Signal Transduction

Staurosporine

fms-Like Tyrosine Kinase 3

Source

Identifiers

PMID: 16503833
DOI: 10.1517/14728214.11.1.153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-16503833-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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