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Article

Review article: liver disease in adults with variants in the cholestasis-related genes ABCB11, ABCB4 and ATP8B1.

Alimentary pharmacology & therapeutics - 1 Dec 2020

Nayagam Jeremy S, Williamson Catherine, Joshi Deepak, Thompson Richard J

Abstract excerpt

BACKGROUND: Children with intrahepatic cholestasis and genetic variants which result in the disruption of the formation and maintenance of bile (ABCB11, ABCB4 and ATP8B1) generally have a rapidly progressive clinical course. Adults with different phenotypes of cholestasis are increasingly being evaluated for variants in these genes associated with childhood diseases. AIMS: To review the literature with respect to...

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Source

Identifiers

PMID: 33070363
DOI: 10.1111/apt.16118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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