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Article

ABCB4 and ABCB11 mutations in intrahepatic cholestasis of pregnancy in an Italian population.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Mar 2013

Anzivino Claudia, Odoardi Maria Rosaria, Meschiari Erica, Baldelli Enrica, Facchinetti Fabio, Neri Isabella, Ruggiero Giuseppe, Zampino Rosa, Bertolotti Marco, Loria Paola, Carulli Lucia

Abstract excerpt

BACKGROUND: Genetic alterations in the ATP-binding cassette subfamily B member 4 (ABCB4) and ATP-binding cassette subfamily B member 11 (ABCB11) have been associated to the onset of intrahepatic cholestasis of pregnancy (ICP) in predisposed women. AIMS: To identify new and/or frequent ABCB4 and ABCB11 genes variants in a cohort of Italian patients with ICP and to evaluate the possible pathogenetic role for the...

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Topics

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Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP-Binding Cassette Transporters

Share to Cholestasis, Intrahepatic

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Source

Identifiers

PMID: 23022423
DOI: 10.1016/j.dld.2012.08.011

Genes

ABCB4
ABCB11

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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