Article
Elevated HMGA2 expression is associated with cancer aggressiveness and predicts poor outcome in breast cancer.
Cancer letters - 1 Jul 2016
Wu Jingjing, Zhang Shizhen, Shan Jinlan, Hu Zujian, Liu Xiyong, Chen Lirong, Ren Xingchang, Yao Lifang, Sheng Hongqiang, Li Ling, Ann David, Yen Yun, Wang Jian, Wang Xiaochen
Abstract excerpt
High mobility group AT-hook 2 (HMGA2) is involved in a wide spectrum of biological processes and is upregulated in several tumors. Here, we collected 273 breast cancer (BC) specimens as a training set and 310 specimens as a validation set to examine the expression of HMGA2 by immunohistochemical staining. It was found that HMGA2 expression was significantly positively correlated with advanced tumor grade and poor...
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