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Article

Epigenetic mechanisms underlying maternal diabetes-associated risk of congenital heart disease.

JCI insight - 19 Oct 2017

Basu Madhumita, Zhu Jun-Yi, LaHaye Stephanie, Majumdar Uddalak, Jiao Kai, Han Zhe, Garg Vidu

Abstract excerpt

Birth defects are the leading cause of infant mortality, and they are caused by a combination of genetic and environmental factors. Environmental risk factors may contribute to birth defects in genetically susceptible infants by altering critical molecular pathways during embryogenesis, but experimental evidence for gene-environment interactions is limited. Fetal hyperglycemia associated with maternal diabetes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperglycemia

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Source

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Identifiers

PMID: 29046480
DOI: 10.1172/jci.insight.95085
PMCID: PMC5846898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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