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Article

Inter-tumor genomic heterogeneity of breast cancers: comprehensive genomic profile of primary early breast cancers and relapses.

Breast cancer research : BCR - 15 Oct 2020

Fumagalli Caterina, Ranghiero Alberto, Gandini Sara, Corso Federica, Taormina Sergio, De Camilli Elisa, Rappa Alessandra, Vacirca Davide, Viale Giuseppe, Guerini-Rocco Elena, Barberis Massimo

Abstract excerpt

BACKGROUND: The breast cancer genome dynamically evolves during malignant progression and recurrence. We investigated the genomic profiles of primary early-stage breast cancers and matched relapses to elucidate the molecular underpinnings of the metastatic process, focusing on potentially actionable alterations in the recurrences. METHODS: A mono-institutional cohort of 128 patients with breast cancers (n = 68...

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Identifiers

PMID: 33059724
DOI: 10.1186/s13058-020-01345-z
PMCID: PMC7566144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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