Genomic characterization and tumor evolution in paired samples of metaplastic breast carcinoma.

doi:10.1038/s41379-022-01017-7

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Genomic characterization and tumor evolution in paired samples of metaplastic breast carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2022

Stradella Agostina, Gargallo Pablo, Cejuela Mónica, Petit Anna, Bosch-Schips Jan, Carbonell Paula, Recalde Sabela, Vethencourt Andrea, Fernandez-Ortega Adela, Falo Catalina, Gil-Gil Miguel, Vázquez Silvia, Obadia Verónica, Villanueva-Vázquez Rafael, Soler-Monsó Teresa, Calabria Inés, Pernas Sonia

Abstract excerpt

Metaplastic breast carcinomas are a rare and heterogeneous group of tumors (0.5-2%). They are mainly triple negative tumors but they present poorer chemotherapy responses and worse prognosis than other triple negative tumors. The aim of our study was to characterize the molecular profile and tumor evolution in matched (primary-relapse) tumor samples from patients with early-stage metaplastic breast carcinomas who...

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PMID: 35177782
DOI: 10.1038/s41379-022-01017-7

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