Dietary factors and polymorphisms in vitamin D metabolism genes: the risk and prognosis of colorectal cancer in northeast China.

doi:10.1038/s41598-017-09356-1

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Dietary factors and polymorphisms in vitamin D metabolism genes: the risk and prognosis of colorectal cancer in northeast China.

Scientific reports - 18 Aug 2017

Gong Chen, Long Zhiping, Yu Yanming, Zhu Lin, Tian Jingshen, Li Shuo, Li Jing, Yu Hongyuan, Chi Qiang, Piao Daxun, Wang Fan, Zhao Yashuang, Cui Binbin

Abstract excerpt

CYP24A1 and CYP27B1 are critical genes determining 1α,25(OH)2D3 concentration and impacting on carcinogenesis. A case-control study including 528 colorectal cancer (CRC) patients and 605 cancer-free controls and a follow-up study with 317 cases were conducted in northeast China. Genotypes were tested by TaqMan Genotyping Assays. Individuals carrying the GG genotype of CYP27B1 G > T (rs10877012) exhibited...

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PMID: 28821819
DOI: 10.1038/s41598-017-09356-1
PMCID: PMC5562792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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