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Streamlined Subpopulation, Subtype, and Recombination Analysis of HIV-1 Half-Genome Sequences Generated by High-Throughput Sequencing.

mSphere - 14 Oct 2020

Hora Bhavna, Gulzar Naila, Chen Yue, Karagiannis Konstantinos, Cai Fangping, Su Chang, Smith Krista, Simonyan Vahan, Shah Sharaf Ali, Ahmed Manzoor, Sanchez Ana M, Stone Mars, Cohen Myron S, Denny Thomas N, Mazumder Raja, Gao Feng

Abstract excerpt

High-throughput sequencing (HTS) has been widely used to characterize HIV-1 genome sequences. There are no algorithms currently that can directly determine genotype and quasispecies population using short HTS reads generated from long genome sequences without additional software. To establish a robust subpopulation, subtype, and recombination analysis workflow, we amplified the HIV-1 3'-half genome from plasma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33055255
DOI: 10.1128/mSphere.00551-20
PMCID: PMC7565892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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