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Article

Significance of druggable targets (PD-L1, KRAS, BRAF, PIK3CA, MSI, and HPV) on curatively resected esophageal squamous cell carcinoma.

Diagnostic pathology - 14 Oct 2020

Lee Hong Kyu, Kwon Mi Jung, Ra Yong Joon, Lee Hee Sung, Kim Hyoung Soo, Nam Eun Sook, Cho Seong Jin, Park Hye-Rim, Min Soo Kee, Seo Jinwon, Choe Ji-Young, Min Kyueng-Whan, Kang So Young

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) still remains intractable disease with few therapeutic options. Programmed death-ligand 1 (PD-L1), which is essential for immune evasion, is involved in the pathogenesis of ESCC and thus is a potential therapeutic target. PIK3CA, KRAS, and BRAF mutations, microsatellite instability (MSI) caused by deficient mismatch repair (dMMR), and human papillomavirus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33054840
DOI: 10.1186/s13000-020-01045-4
PMCID: PMC7557072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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