Article
PD-L1 Expression Promotes Epithelial to Mesenchymal Transition in Human Esophageal Cancer.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2017
Chen Lujun, Xiong Yuqi, Li Jing, Zheng Xiao, Zhou Qi, Turner Abbey, Wu Changping, Lu Binfeng, Jiang Jingting
Abstract excerpt
BACKGROUND/AIMS: PD-L1 (Programmed cell death 1 ligand 1, PD-L1), an essential immune checkpoint molecule in the tumor microenvironment, is an important target for cancer immunotherapy. We have previously reported that its expression in human gastric and esophageal cancer tissues is significantly associated with cancer progression and patients' postoperative prognoses. Its expression in cancer cells is well known...
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