Article
Tumor immune microenvironment and immune checkpoint inhibitors in esophageal squamous cell carcinoma.
Cancer science - 1 Sept 2020
Baba Yoshifumi, Nomoto Daichi, Okadome Kazuo, Ishimoto Takatsugu, Iwatsuki Masaaki, Miyamoto Yuji, Yoshida Naoya, Baba Hideo
Abstract excerpt
Esophageal squamous cell carcinoma (ESCC) is the main prevalent histological type of esophageal cancer, predominantly constituting 90% of cases worldwide. Despite the development of multidisciplinary therapeutic approaches, its prognosis remains unfavorable. Recently, the development of monoclonal antibodies inhibiting programmed death 1 (PD-1) or programmed death-ligand 1 (PD-L1) has led to marked therapeutic...
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