Article
Prognostic Significance of the MAD1L1 1673 G: A Polymorphism in Ovarian Adenocarcinomas.
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion - 22 Dec 2020
Bandala-Jacques Antonio, Hernández-Cruz Irwin A, Castro-Hernández Clementina, Díaz-Chávez José, Arriaga-Canon Cristian, Barquet-Muñoz Salim A, Prada-Ortega Diddier G, Cantú-de León David, Herrera Luis A
Abstract excerpt
BACKGROUND: Ovarian cancer is the most lethal gynecologic cancer. Although most patients respond adequately to the first-line therapy, up to 85% experience a recurrence of disease, which carries a poor prognosis. Mitotic arrest deficiency 1 is a protein that helps in the assembly of the mitotic spindle assembly checkpoint by preventing anaphase until all chromatids are properly aligned. A single-nucleotide...
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