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Article

Mitotic checkpoint gene MAD1 in hepatocellular carcinoma is associated with tumor recurrence after surgical resection.

Journal of surgical oncology - 1 Jun 2008

Nam Chang Woo, Park Neung Hwa, Park Bo Ryung, Shin Jung Woo, Jung Seok Won, Na Yang Won, Seo Jae Hee

Abstract excerpt

OBJECTIVE: Underlying mechanism of mitotic checkpoint gene mitosis arrest deficiency 1 (MAD1) in human hepatocellular carcinoma (HCC) is rarely known. MATERIALS AND METHODS: We studied genetic change of the MAD1 gene as well as protein expression in 44 HCC and their associated non-cancerous surrounding liver tissues. RESULTS: Genotype AG of MAD1 G-1849 A promoter was highly significant in microscopic vascular...

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Identifiers

PMID: 18491369
DOI: 10.1002/jso.20999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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