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Article

Mutations in the mitotic check point gene, MAD1L1, in human cancers.

Oncogene - 31 May 2001

Tsukasaki K, Miller C W, Greenspun E, Eshaghian S, Kawabata H, Fujimoto T, Tomonaga M, Sawyers C, Said J W, Koeffler H P

Abstract excerpt

Aneuploidy is a characteristic of the majority of human cancers, and recent studies suggest that defects of mitotic checkpoints play a role in carcinogenesis. MAD1L1 is a checkpoint gene, and its dysfunction is associated with chromosomal instability. Rare mutations of this gene have been reporte...

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Identifiers

PMID: 11423979
DOI: 10.1038/sj.onc.1204421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11423979-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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