Article
Exploration into biomarker potential of region-specific brain gene co-expression networks.
Scientific reports - 13 Oct 2020
Hang Yuqing, Aburidi Mohammed, Husain Benafsh, Hickman Allison R, Poehlman William L, Feltus F Alex
Abstract excerpt
The human brain is a complex organ that consists of several regions each with a unique gene expression pattern. Our intent in this study was to construct a gene co-expression network (GCN) for the normal brain using RNA expression profiles from the Genotype-Tissue Expression (GTEx) project. The brain GCN contains gene correlation relationships that are broadly present in the brain or specific to thirteen brain...
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