Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD).

doi:10.3390/cells9102257

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD).

Cells - 8 Oct 2020

Kiel Christina, Strunz Tobias, International Amd Genomics Consortium Project Manager Susan Blanton Iamdgc, Grassmann Felix, Weber Bernhard H F

Abstract excerpt

Genome-wide association studies (GWAS) have identified an abundance of genetic loci associated with complex traits and diseases. In contrast, in-depth characterization of an individual genetic signal is rarely available. Here, we focus on the genetic variant rs2168518 in 15q24.1 previously associated with age-related macular degeneration (AMD), but only with suggestive evidence. In a two-step procedure, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Choroidal Neovascularization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 15

Share to Databases, Genetic

Share to Genetic Loci

Share to Genetic Pleiotropy

Share to Macular Degeneration

Share to MicroRNAs

Share to Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 33050031
DOI: 10.3390/cells9102257
PMCID: PMC7650707

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD).PMID 33050031Read ↗

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits.Semantic proximity Read ↗

Learning from Fifteen Years of Genome-Wide Association Studies in Age-Related Macular Degeneration.Semantic proximity Read ↗

The Role of Gene Expression Regulation on Genetic Risk of Age-Related Macular Degeneration.Semantic proximity Read ↗

Genome-wide analysis of genetic pleiotropy and causal genes across three age-related ocular disordersSemantic proximity Read ↗

Functional genomics in age-related macular degeneration: From genetic associations to understanding disease mechanisms.Semantic proximity Read ↗

Transcriptome-wide association implicates <i>HTRA1-AS1</i> in age-related macular degeneration riskSemantic proximity Read ↗

Genome-wide analysis of genetic pleiotropy and causal genes across three age-related ocular disorders.Semantic proximity Read ↗

Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis.Semantic proximity Read ↗

The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.Semantic proximity Read ↗

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration.Semantic proximity Read ↗

Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation.Semantic proximity Read ↗

Statistical driver genes as a means to uncover missing heritability for age-related macular degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.