Article
Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer.
Oncotarget - 28 Jun 2016
Jadaliha Mahdieh, Zong Xinying, Malakar Pushkar, Ray Tania, Singh Deepak K, Freier Susan M, Jensen Tor, Prasanth Supriya G, Karni Rotem, Ray Partha S, Prasanth Kannanganattu V
Abstract excerpt
MALAT1 (metastasis associated lung adenocarcinoma transcript1) is a conserved long non-coding RNA, known to regulate gene expression by modulating transcription and post-transcriptional pre-mRNA processing of a large number of genes. MALAT1 expression is deregulated in various tumors, including breast cancer. However, the significance of such abnormal expression is yet to be fully understood. In this study, we...
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