Exploring causal correlations between inflammatory proteins and Bullous pemphigoid：bi-directional mendelian randomisation study

Abstract excerpt

Bullous pemphigoid (BP), the most common autoimmune bullous disease, typically presents with generalized crops of tense, pruritic cutaneous blisters and mostly affects the elderly, Here, we aimed to figure out the interplay between peripheral inflammatory proteins and BP. Based on publicly available genetic data, bidirectional Mendelian randomization (MR) analysis was performed to determine the causal association...

Topics

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• Dyslipidemias
• Genome-Wide Association Study
• Glucose Intolerance
• Hypertension
• Mendelian Randomization Analysis
• Metabolic Syndrome
• Pemphigoid, Bullous
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

72ba25f6-fb87-5ef9-b150-a48cf8860e2c

DOI

10.22541/au.171072203.38072382/v1