Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inflammation and mitophagy are mitochondrial checkpoints to aging

20 Apr 2024

Abstract excerpt

Cellular and organismal aging have been consistently associated with mitochondrial dysfunction and inflammation. Accumulating evidence indicates that aging-related inflammatory responses are mechanistically linked to compromised mitochondrial integrity coupled with mtDNA-driven CGAS activation, a process that is tonically inhibited by mitophagy. Cellular and organismal aging have been consistently associated with...

Topics

Join the communities discussing this publication.

Autophagy in Disease and Therapy
MicroRNA in disease regulation
Mitochondrial Function and Pathology

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38643254
DOI: 10.1038/s41467-024-47840-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inflammation and mitophagy are mitochondrial checkpoints to agingPMID 38643254Read ↗

Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal AgingSemantic proximity Read ↗

Mitophagy in relation to chronic inflammation/ROS in agingSemantic proximity Read ↗

Mitophagy in aging and longevitySemantic proximity Read ↗

Mitophagy: An Emerging Role in Aging and Age-Associated DiseasesSemantic proximity Read ↗

Role of mitophagy in the hallmarks of agingSemantic proximity Read ↗

Mitophagy and DNA damage signaling in human agingSemantic proximity Read ↗

Role of the mtDNA Mutations and Mitophagy in Inflammaging.Semantic proximity Read ↗

Mitophagy: A crucial modulator in the pathogenesis of chronic diseasesSemantic proximity Read ↗

Mitophagy and Neuroinflammation: A Compelling InterplaySemantic proximity Read ↗

Mitophagy in health and disease. Molecular mechanisms, regulatory pathways, and therapeutic implicationsSemantic proximity Read ↗

Aging Hallmarks and the Role of Oxidative StressSemantic proximity Read ↗

Mitophagy and cGAS–STING crosstalk in neuroinflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.