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Mitochondrial DNA: Bridging cellular senescence and chronic inflammation in aging and beyond.

Mutation research. Reviews in mutation research - 1 Jan 2026

Wang Shimeng, Wu Fanglong, Zhou Hongmei

Abstract excerpt

Aging is a progressive and irreversible physiological process driven by a complex network of interrelated molecular and cellular mechanisms. Among these, cellular senescence and chronic inflammation, as two core hallmarks of aging, are interlinked and jointly promote the development and progression of aging. However, the precise molecular crosstalk between these two processes remains unclarified. Mitochondrial...

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Aging
Cellular Senescence
DNA, Mitochondrial
Inflammation
Mitochondria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oxidative Stress

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PMID: 41849986
DOI: 10.1016/j.mrrev.2026.108587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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