Article
Genetic alterations in non-syndromic, familial gliomas in first degree relatives: A systematic review.
Clinical neurology and neurosurgery - 1 Nov 2020
Vasilica Anca-Mihaela, Sefcikova Viktoria, Samandouras George
Abstract excerpt
OBJECTIVE: Despite numerous reports in syndromic gliomas, the underlying genetic and molecular basis of familial, non-syndromic gliomas, in first degree relatives, remains unclear. This rare cohort of patients harboring invasive primary brain tumors with poor prognosis may provide a potential substrate of understanding the complex genetic cascade triggering tumorigenesis. METHODS: A systematic review was...
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