Article
A Comparative Study of the Molecular Characteristics of Familial Gliomas and Other Cancers.
Cancer genomics & proteomics - 1 Jan 2000
Lu Jie, Burnett Mark G, Shpak Max
Abstract excerpt
BACKGROUND: Familial cancers are those that co-occur among first-degree relatives without showing Mendelian patterns of inheritance. MATERIALS AND METHODS: In this analysis, we compare the genomic characteristics of familial and sporadic cancers, with a focus on low-grade gliomas (LGGs) using sequence and expression data from the Cancer Genome Atlas. RESULTS: Familial cancers show similar genomic and molecular...
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