Article
A Mutation in the Drosophila melanogaster eve Stripe 2 Minimal Enhancer Is Buffered by Flanking Sequences.
G3 (Bethesda, Md.) - 3 Dec 2020
López-Rivera Francheska, Foster Rhoades Olivia K, Vincent Ben J, Pym Edward C G, Bragdon Meghan D J, Estrada Javier, DePace Angela H, Wunderlich Zeba
Abstract excerpt
Enhancers are DNA sequences composed of transcription factor binding sites that drive complex patterns of gene expression in space and time. Until recently, studying enhancers in their genomic context was technically challenging. Therefore, minimal enhancers, the shortest pieces of DNA that can drive an expression pattern that resembles a gene's endogenous pattern, are often used to study features of enhancer...
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