Article
Diffuse expression of MUC6 defines a distinct clinicopathological subset of pulmonary invasive mucinous adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2021
Kishikawa Satsuki, Hayashi Takuo, Saito Tsuyoshi, Takamochi Kazuya, Kohsaka Shinji, Sano Kei, Sasahara Noriko, Sasa Keita, Kurihara Taisei, Hara Kieko, Suehara Yoshiyuki, Takahashi Fumiyuki, Suzuki Kenji, Yao Takashi
Abstract excerpt
Invasive mucinous adenocarcinoma (IMA) of the lung is a unique variant of lung adenocarcinoma. Aberrant mucin expression is associated with cancer development and metastasis. However, the clinicopathological significance of mucin expression in IMA is not fully understood. Herein, we evaluated the clinicopathological, immunohistochemical, and molecular characteristics of 70 IMA tumors. EGFR, KRAS, GNAS, and TP53...
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