Article
Pulmonary adenocarcinoma with enteric differentiation: Dissecting oncogenic genes alterations with DNA sequencing and FISH analysis.
Experimental and molecular pathology - 1 Apr 2017
Nottegar Alessia, Tabbò Fabrizio, Luchini Claudio, Guerrera Francesco, Gaudiano Marcello, Bria Emilio, Brunelli Matteo, Chilosi Marco, Inghirami Giorgio
Abstract excerpt
BACKGROUND: Pulmonary Adenocarcinoma with Enteric Differentiation (PAED) is a rare subtype of adenocarcinoma of emerging interest, recently introduced in the 2015 WHO classification. However, little is known about major molecular signatures of this class of adenocarcinomas and information about new biomarkers totally lack. METHODS: We examined the NRAS, PIK3CA, EGFR, KRAS and BRAF status through mass spectrometry...
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