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CancerImmunityQTL: a database to systematically evaluate the impact of genetic variants on immune infiltration in human cancer.

Nucleic acids research - 8 Jan 2021

Tian Jianbo, Cai Yimin, Li Yue, Lu Zequn, Huang Jinyu, Deng Yao, Yang Nan, Wang Xiaoyang, Ying Pingting, Zhang Shanshan, Zhu Ying, Zhang Huilan, Zhong Rong, Chang Jiang, Miao Xiaoping

Abstract excerpt

Tumor-infiltrating immune cells as integral component of the tumor microenvironment are associated with tumor progress, prognosis and responses to immunotherapy. Genetic variants have been demonstrated to impact tumor-infiltrating, underscoring the heritable character of immune landscape. Therefore, identification of immunity quantitative trait loci (immunQTLs), which evaluate the effect of genetic variants on...

Topics

Data Mining
Databases, Genetic
Gene Expression Regulation, Neoplastic
Genome-Wide Association Study
Genotype
Humans
Immunity
Internet
Linkage Disequilibrium
Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Prognosis

Quantitative Trait Loci

Tumor Microenvironment

User-Computer Interface

Source

Open in PubMed Open full text

Identifiers

PMID: 33010176
DOI: 10.1093/nar/gkaa805
PMCID: PMC7778991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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