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TIMER2.0 for analysis of tumor-infiltrating immune cells

17 May 2020

Abstract excerpt

Tumor progression and the efficacy of immunotherapy are strongly influenced by the composition and abundance of immune cells in the tumor microenvironment. Due to the limitations of direct measurement methods, computational algorithms are often used to infer immune cell composition from bulk tumor transcriptome profiles. These estimated tumor immune infiltrate populations have been associated with genomic and...

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PMID: 32442275
DOI: 10.1093/nar/gkaa407

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