Article
Polymorphisms in the fibrinolytic pathway genes and the risk of recurrent spontaneous abortion.
Reproductive biomedicine online - 1 Dec 2014
Andraweera Prabha H, Dekker Gustaaf A, Thompson Steven D, Nowak Rachael C, Jayasekara Rohan W, Dissanayake Vajira H W, Roberts Claire T
Abstract excerpt
Impaired fibrinolytic activity is implicated in the pathogenesis of recurrent spontaneous abortion (RSA). This case-control study assessed the prevalence of polymorphisms in fibrinolytic system genes in RSA. Cases comprised 202 Sinhalese women who had experienced at least two first-trimester spontaneous abortions and had no living children; controls were 202 women with no history of spontaneous abortion and two...
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