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Active Cigarette Smoking Is Associated With an Exacerbation of Genetic Susceptibility to Diabetes.

Diabetes - 1 Dec 2020

Lin Wan-Yu, Liu Yu-Li, Yang Albert C, Tsai Shih-Jen, Kuo Po-Hsiu

Abstract excerpt

The heritability levels of two traits for diabetes diagnosis, serum fasting glucose (FG) and glycated hemoglobin (HbA1c), were estimated to be 51-62%. Studies have shown that cigarette smoking is a modifiable risk factor for diabetes. It is important to uncover whether smoking may modify the genetic risk of diabetes. This study included unrelated Taiwan Biobank subjects in a discovery cohort (TWB1) of 25,460...

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Identifiers

PMID: 33004471
DOI: 10.2337/db20-0156

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