Article
An association study of C9orf3, a novel component of the renin-angiotensin system, and hypertension in diabetes.
Scientific reports - 30 Sept 2020
Ichikawa Mai, Konoshita Tadashi, Makino Yasukazu, Suzuki Jinya, Ishizuka Tamotsu, Nakamura Hiroyuki
Abstract excerpt
The renin-angiotensin system (RAS) is important in the onset and course of cardiovascular, kidney, and metabolic disorders. Previous reports showed that the RAS blockade protects organs and suppress the development of type 2 diabetes mellitus. A novel component of the RAS, namely, chromosome 9 open reading frame 3 (C9orf3), was recently identified, however, its effects are unclear. We evaluated whether the...
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