Article
PDIA3 rs2788: An Independent Risk Factor for Hypertension and Its Interaction With Antihypertensive Medications.
Journal of clinical hypertension (Greenwich, Conn.) - 1 Jan 2025
Lan Hongtao, Xi Yingbin, Kang Baoxu, Tong Zhoujie, Peng Jie, Zhang Wei, Zhong Ming, Gong Huiping, Wang Zhihao
Abstract excerpt
Hypertension is a multifactorial condition influenced by both genetic and environmental factors. Protein disulfide isomerase family A member 3 (PDIA3) is a key endoplasmic reticulum protein which may contribute to increased blood pressure. However, the relationship between PDIA3 polymorphisms and hypertension remain unclear. This study aims to explore the relationship between PDIA3 polymorphisms and hypertension....
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