Article
Association between Cullin-3 Single-Nucleotide Polymorphism rs17479770 and Essential Hypertension in the Male Chinese Han Population.
Disease markers - 1 Jan 2017
Li Jin, Hu Jing, Sun Rong, Zhao Yongpan, Liu Heping, Li Jian, Shi Lei, Zhao Shujin
Abstract excerpt
BACKGROUND: Hypertension, including essential and secondary hypertension, is a multifactorial disease, affecting more than one billion people worldwide. Secondary hypertension can result from mutations of cullin-3 (CUL3); however, whether polymorphisms of CUL3 are associated with essential hypertension (EH) has not been reported. Here, we investigated the association between CUL3 SNPs rs17479770 and rs3738952 and...
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