Article
Genetic variants in long noncoding RNA H19 and MEG3 confer risk of type 2 diabetes in an Iranian population.
Gene - 30 Oct 2018
Ghaedi Hamid, Zare Ali, Omrani Mir Davood, Doustimotlagh Amir Hossein, Meshkani Reza, Alipoor Sadegh, Alipoor Behnam
Abstract excerpt
PURPOSE: Long-noncoding RNAs (lncRNAs) have been reported to regulate glucose homeostasis and insulin synthesis and secretion. However, the association of genetic variants of lncRNAs and type 2 diabetes (T2D) has not been evaluated. Therefore, in the present study we investigated the association between H19 rs217727 and H19 rs3741219 variants and MEG3 rs7158663 polymorphism with T2D susceptibility. MATERIALS AND...
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