Article
Generation and Validation of the iKp1289 Metabolic Model for Klebsiella pneumoniae KPPR1.
The Journal of infectious diseases - 15 Feb 2017
Henry Christopher S, Rotman Ella, Lathem Wyndham W, Tyo Keith E J, Hauser Alan R, Mandel Mark J
Abstract excerpt
Klebsiella pneumoniae has a reputation for causing a wide range of infectious conditions, with numerous highly virulent and antibiotic-resistant strains. Metabolic models have the potential to provide insights into the growth behavior, nutrient requirements, essential genes, and candidate drug targets in these strains. Here we develop a metabolic model for KPPR1, a highly virulent strain of K. pneumoniae. We...
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