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Article

The Anticancer Potential of T Cell Receptor-Engineered T Cells.

Trends in cancer - 1 Jan 2021

Ecsedi Matyas, McAfee Megan S, Chapuis Aude G

Abstract excerpt

Adoptively transferred T cell receptor (TCR)-transgenic T cells (TCR-T cells) are not restricted by cell surface expression of their targets and are therefore poised to become a main pillar of cellular cancer immunotherapies. Addressing clinical and laboratory data, we discuss emerging features for the efficient deployment of novel TCR-T therapies, such as selection of ideal TCRs targeting validated epitopes with...

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Source

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Identifiers

PMID: 32988787
DOI: 10.1016/j.trecan.2020.09.002
PMCID: PMC7770096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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