Article
Sleep problems in Rett syndrome animal models: A systematic review.
Journal of neuroscience research - 1 Feb 2021
Zhang Xinyan, Lin Jian-Sheng, Spruyt Karen
Abstract excerpt
Due to the discovery of Rett Syndrome (RTT) genetic mutations, animal models have been developed. Sleep research in RTT animal models may unravel novel neural mechanisms for this severe neurodevelopmental heritable rare disease. In this systematic literature review we summarize the findings on sleep research of 13 studies in animal models of RTT. We found disturbed efficacy and continuity of sleep in all...
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