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Article

CDKL5 deficiency entails sleep apneas in mice.

Journal of sleep research - 1 Aug 2017

Lo Martire Viviana, Alvente Sara, Bastianini Stefano, Berteotti Chiara, Silvani Alessandro, Valli Alice, Viggiano Rocchina, Ciani Elisabetta, Zoccoli Giovanna

Abstract excerpt

A recently discovered neurodevelopmental disorder caused by the mutation of the cyclin-dependent kinase-like 5 gene (CDKL5) entails complex autistic-like behaviours similar to Rett syndrome, but its impact upon physiological functions remains largely unexplored. Sleep-disordered breathing is common and potentially life-threatening in patients with Rett syndrome; however, evidence is limited in children with CDKL5...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28230307
DOI: 10.1111/jsr.12512

Genes

CDKL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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