Article
Whence Blobs? Phylogenetics of functional protein condensates.
Biochemical Society transactions - 30 Oct 2020
Pritišanac Iva, Zarin Taraneh, Forman-Kay Julie D, Moses Alan M
Abstract excerpt
What do we know about the molecular evolution of functional protein condensation? The capacity of proteins to form biomolecular condensates (compact, protein-rich states, not bound by membranes, but still separated from the rest of the contents of the cell) appears in many cases to be bestowed by weak, transient interactions within one or between proteins. Natural selection is expected to remove or fix amino acid...
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