Article
Geometric evolutionary dynamics of protein interaction networks.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2010
Przulj Natasa, Kuchaiev Oleksii, Stevanović Aleksandar, Hayes Wayne
Abstract excerpt
Understanding the evolution and structure of protein-protein interaction (PPI) networks is a central problem of systems biology. Since most processes in the cell are carried out by groups of proteins acting together, a theoretical model of how PPI networks develop based on duplications and mutations is an essential ingredient for understanding the complex wiring of the cell. Many different network models have...
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